MSCI's gauge of stocks across the globe fell 6.14 points, or 0.70%, to 869.20.
The STOXX 600 index fell 0.38%, while Europe's broad FTSEurofirst 300 index fell 8.54 points, or 0.39% Emerging market stocks rose 4.06 points, or 0.37%, to 1,106.31. MSCI's broadest index of Asia-Pacific shares outside Japan closed higher by 0.39%, to 582.30, while Japan's Nikkei fell 279.51 points, or 0.72%, to 38,787.02.
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